[{"accession_id":"EGAD50000000475","title":"Osteosarcoma WGS on multiple tissue samples from six patients","description":"Osteosarcoma is a primary bone tumor that exhibits a complex genome characterized by gross chromosomal abnormalities. Osteosarcoma patients often develop metastatic disease, resulting in limited therapeutic options and poor survival rates. To gain knowledge on the mechanisms underlying osteosarcoma heterogeneity and metastatic process, it is important to obtain a detailed profile of the genomic alterations that accompany osteosarcoma progression. Therefore, in this study we performed WGS on multiple tissue samples from six patients with osteosarcoma, including the treatment naïve biopsy of the primary tumor, resection of the primary tumor after neoadjuvant chemotherapy, local recurrence and distant metastases. ","dataset_types":["Whole genome sequencing"],"technologies":["Illumina NovaSeq 6000"],"num_samples":30,"access_type":"controlled","is_in_beacon":false,"is_released":true,"released_date":"2024-08-02T08:36:53.052784+02:00","is_deprecated":false,"policy_accession_id":"EGAP50000000197"}]